Global Senior Program Manager R&D

As a member of Alfasigma’s Global Program Management Office, the Program Manager contributes to the management of the company’s development programs and supports operational pipeline activities. This role ensures accurate project management information, monitors progress, identifies potential issues, and advises the Core Program Team on mitigative actions. The Program Manager collaborates closely with representatives from multiple departments—including Research, Non-clinical, CMC, Regulatory Affairs, and Clinical—placing them in a central position to manage cross-functional dependencies and report directly to the Program Director.

Scope of the Role

As a member of Alfasigma’s Global Program Management Office, the Program Manager contributes to the management of the company’s development programs and supports operational pipeline activities. This role ensures accurate project management information, monitors progress, identifies potential issues, and advises the Core Program Team on mitigative actions. The Program Manager collaborates closely with representatives from multiple departments—including Research, Non-clinical, CMC, Regulatory Affairs, and Clinical—placing them in a central position to manage cross-functional dependencies and report directly to the Program Director.

Your Role

• Support the Program Director (PD) in leading the R&ED portfolio as a key liaison between functional sub-teams, program members, and other organizational units, including alliance partners when applicable.
• Prepare and lead select Pre-clinical Global Program Team meetings, with PD support.
• Develop high-level and detailed project schedules, support program budget development, set baselines for new projects and phases, and provide timely alerts and solutions to the PD regarding variances.
• Monitor program sub-team deliverables to ensure execution aligns with strategy and functional plans; track milestones and deliverables.
• Support program reporting, collecting and analyzing project performance data including timelines, budgets/resources, and other relevant metrics.
• Lead the risk management process, including proactive risk identification, quantification, mitigation planning, and strategy definition.
• Contribute to project strategy development, ensuring it is translated into robust and realistic project plans in collaboration with all relevant functions and the PD.
• Assist in preparing presentations for senior management committees in partnership with the PD and other stakeholders.

Who You Are

• Proficient in project management software (MS Project or equivalent).
• Team player with excellent organizational, communication, and interpersonal skills across diverse functions.
• Strong sense of urgency and patient centricity.
• Able to work effectively under pressure, adaptable and flexible, maintaining a positive outlook.
• Proactive and creative thinker, willing to challenge the status quo.
• Fluent in English.

Education & Background

• Degree in a scientific discipline (BS, MS, Engineering, PhD, DVM).
• Minimum 3 years’ experience in project management or planning, preferably in pharmaceutical or biotech industries.
• Knowledge of all phases of drug development, from Discovery to Commercial.
• Project management training or formal qualification is desirable; PMP certification is a plus.