Technician/Senior Technician in Functional Genomics and ‘Omics Technologies – HT Flagship Research Programme for Immunogenomics and Cancer

APPLICATION CLOSING DATE: September 7th, 2025

Application Instructions

Please apply forwarding a single document containing

I) a CV

II) a motivation letter in English

III) names and contacts of 2 referees

Only for general enquires concerning the role, please contact: (this email address should not be used to send applications).

About Human Technopole:

Human Technopole (HT) is an interdisciplinary life science research institute, created and supported by the Italian government, with the aim of developing innovative strategies to improve human health. Researchers at HT work together to enable interdisciplinary research and to create an open, collaborative environment that will help promote life science research both nationally and internationally.

Flagship Research Programmes at HT are strategic collaborative efforts that leverage on the cutting-edge expertise and infrastructure available at HT for translational research focussed on different human pathologies.

In the “Immunogenomics & Cancer” Flagship Research Programme we will investigate immune diseases and tumours as evolving systems and use multi-modal data through spatiotemporal scales, including functional genomics assays, to understand why and how those diseases change over time. We will also tackle the question of what are the mechanisms by which those diseases stop responding to treatment, developing drug resistance.

About the position:

The Immunogenomics & Cancer Flagship Research Programme at Human Technopole (HT) is seeking a skilled and motivated Research Technician/Senior Research Technician to generate novel ‘omics data from appropriate models, including patient-derived organoids and primary cell cultures.

The successful candidate will be responsible for optimising, implementing and applying novel functional genomics protocols available within HT’s Functional Genomics Research Centre, such as bulk and single-cell based 3D genome technologies (e.g. Hi-C, Dip-C), as well as CAGE-seq, RADICL-seq, RIBO-seq and others. The role will involve generating high-quality NGS data and contributing to cutting-edge research into cancer and immune-related diseases.

We are looking for a highly organized and detail-oriented candidate with a strong background in molecular biology and hands-on experience in next-generation sequencing (NGS) and library preparation.

The ideal candidate will have experience in applying ‘omics techniques in research setting and be confident working with human-derived samples. They will work collaboratively with experimental and computational scientists at HT and contribute to the generation and interpretation of high-quality data, as well as the formulation and validation of hypotheses.

The role offers the opportunity to be part of a diverse and interdisciplinary team, supported by the latest technologies within the HT National Genomics Facility.

Key tasks and responsibilities

• Implement and optimize functional genomics methods for ‘omics profiling.
• Work with human samples and human-derived models (e.g., organoids, primary cultures).
• Apply, generate, and optimize protocols and standardize procedures.
• Generate high-quality and reliable NGS libraries for publiations and maintain clear, accurate records of all data and results.
• Collaborate with the HT National Genomics Facility on sample profiling.
• Support and train lab members in (new) molecular and functional genomics techniques.
• Ensure compliance with safety standards, including preparation and regular update of risk assessments in collaboration with Lab Managers.

Job Requirements

Essential requirements:

• Bachelor’s degree in a relevant subject, e.g., molecular biology, genetics, biochemistry, or in a related field of the life sciences.
• Proven expertise in Next-Generation Sequencing library preparation and data generation.
• Considerable experience in laboratories involved in the areas of main responsibilities.
• Fluency in English, the working language at HT.

Preferential requirements:

• Proven hands-on experience applying cutting-edge ‘omics methods.
• Familiarity with working on human-derived samples (e.g., organoids, primary cells).
• Proficiency with a broad range of molecular biology techniques.

Organizational and social skills:

• Ability to manage multiple priorities in a fast-paced research environment.
• Excellent troubleshooting, documentation, and communication skills.
• Collaborative mindset with strong interpersonal skills.
• Commitment to working in a diverse, international research setting.

Why Human Technopole

HT seeks scientific excellence, we recruit the best scientific talents through international, open calls.

Our working environment is international, friendly and inclusive. Our scientists work together across disciplines on research topics of biomedical relevance, leveraging synergies between their diverse skillsets and methodological approaches.

We believe that highly diverse teams yield the best and most innovative results.

We engage in outward-facing scientific activities aimed at benefiting the national and international research community. Training is also at the heart of our activity, with initiatives and opportunities for our staff, including scientific courses, conferences and workshops.

Main benefits

• Meal delivery service.
• Work-life balance provisions.
• Italian language training for foreigners.
• Parental leave up to 1 year and other support for new parents.
• Flexible working hours.
• Support for relocation.
• Tax benefits where applicable
• Welfare plans

Special consideration will be given to candidates who are part of the protected categories list, according to L. 68/99.

Number of positions offered: 1

Location: Milan

Contract offered: CCNL Chimico Farmaceutico, 3 years fixed-term with possibility of renewal - Employee level

Salary range: 35k-41k depending on candidate's seniority.

The Foundation reserves the right, at its sole discretion, to extend, suspend, modify, revoke, or cancel this job posting without giving rise to any rights or claims whatsoever in favour of the candidates; the Foundation reserves, however, the right not to proceed with the awarding of the above-described assignment due to the effect of supervening regulatory provisions and/or obstructive circumstances.